Identification of AR-V7 downstream genes commonly targeted by AR/AR-V7 and specifically targeted by AR-V7 in castration resistant prostate cancer

Primary prostate cancer (PC) progresses to castration-resistant PC (CRPC) under androgen deprivation therapy, by mechanisms e.g. expression of androgen receptor (AR) splice variant-7 (AR-V7). Here we conducted comprehensive epigenome and transcriptome analyses comparing LNCaP, primary PC cells, and...

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Vydáno v:Transl Oncol
Hlavní autoři: Sugiura, Masahiro, Sato, Hiroaki, Okabe, Atsushi, Fukuyo, Masaki, Mano, Yasunobu, Shinohara, Ken-ichi, Rahmutulla, Bahityar, Higuchi, Kosuke, Maimaiti, Maihulan, Kanesaka, Manato, Imamura, Yusuke, Furihata, Tomomi, Sakamoto, Shinichi, Komiya, Akira, Anzai, Naohiko, Kanai, Yoshikatsu, Luo, Jun, Ichikawa, Tomohiko, Kaneda, Atsushi
Médium: Artigo
Jazyk:Inglês
Vydáno: Neoplasia Press 2020
Témata:
Original article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581977/
https://ncbi.nlm.nih.gov/pubmed/33096335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100915
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