Characterization of Fusobacterium varium Fv113-g1 isolated from a patient with ulcerative colitis based on complete genome sequence and transcriptome analysis

par Sekizuka, Tsuyoshi, Ogasawara, Yumiko, Ohkusa, Toshifumi, Kuroda, Makoto
Publié dans PLoS One (2017)

Gut Microbiota and Chronic Constipation: A Review and Update

par Ohkusa, Toshifumi, Koido, Shigeo, Nishikawa, Yuriko, Sato, Nobuhiro
Publié dans Front Med (Lausanne) (2019)

Commensal bacteria can enter colonic epithelial cells and induce proinflammatory cytokine secretion: a possible pathogenic mechanism of ulcerative colitis

par Ohkusa, Toshifumi, Yoshida, Tsutomu, Sato, Nobuhiro, Watanabe, Sumio, Tajiri, Hisao, Okayasu, Isao
Publié 2009

Antigen-Specific Polyclonal Cytotoxic T Lymphocytes Induced by Fusions of Dendritic Cells and Tumor Cells

par Koido, Shigeo, Homma, Sadamu, Hara, Eiichi, Namiki, Yoshihisa, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao
Publié 2010

Cancer Vaccine by Fusions of Dendritic and Cancer Cells

par Koido, Shigeo, Hara, Eiichi, Homma, Sadamu, Namiki, Yoshihisa, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao
Publié 2009

Corticotropin-releasing factor secretion from dendritic cells stimulated by commensal bacteria

par Hojo, Mariko, Ohkusa, Toshifumi, Tomeoku, Harumi, Koido, Shigeo, Asaoka, Daisuke, Nagahara, Akihito, Watanabe, Sumio
Publié 2011

Long-term outcomes of antibiotic combination therapy for ulcerative colitis

par Nishikawa, Yuriko, Sato, Nobuhiro, Tsukinaga, Shintaro, Uchiyama, Kan, Koido, Shigeo, Ishikawa, Dai, Ohkusa, Toshifumi
Publié dans Ther Adv Chronic Dis (2021)

Gastrointestinal stromal tumor of the stomach with a giant abscess penetrating the gastric lumen

par Osada, Taro, Nagahara, Akihito, Kodani, Tomohiro, Namihisa, Akihiro, Kawabe, Masato, Yoshizawa, Takashi, Ohkusa, Toshifumi, Watanabe, Sumio
Publié 2007

Chemoimmunotherapy targeting Wilms’ tumor 1 (WT1)-specific cytotoxic T lymphocyte and helper T cell responses for patients with pancreatic cancer

par Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Takakura, Kazuki, Gong, Jianlin, Sugiyama, Haruo, Ohkusa, Toshifumi, Tajiri, Hisao
Publié dans Oncoimmunology (2014)

Four-week pegylated interferon α-2a monotherapy for chronic hepatitis C with genotype 2 and low viral load: A pilot, randomized study

par Tsubota, Akihito, Satoh, Ken-ichi, Aizawa, Mashu, Takamatsu, Seishi, Namiki, Yoshihisa, Ohkusa, Toshifumi, Fujise, Kiyotaka, Tajiri, Hisao
Publié 2008

A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

par Odahara, Shunichi, Uchiyama, Kan, Kubota, Takahiro, Ito, Zensho, Takami, Shinichiro, Kobayashi, Hiroko, Saito, Keisuke, Koido, Shigeo, Ohkusa, Toshifumi
Publié dans PLoS One (2015)

Advances in inducing adaptive immunity using cell-based cancer vaccines: Clinical applications in pancreatic cancer

par Kajihara, Mikio, Takakura, Kazuki, Kanai, Tomoya, Ito, Zensho, Matsumoto, Yoshihiro, Shimodaira, Shigetaka, Okamoto, Masato, Ohkusa, Toshifumi, Koido, Shigeo
Publié dans World J Gastroenterol (2016)

The combination of TLR2 and TLR4 agonists promotes the immunogenicity of dendritic cell/cancer cell fusions

par Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Namiki, Yoshihisa, Takakura, Kazuki, Uchiyama, Kan, Kajihara, Mikio, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao
Publié 2013

Dendritic cell-based cancer immunotherapy for colorectal cancer

par Kajihara, Mikio, Takakura, Kazuki, Kanai, Tomoya, Ito, Zensho, Saito, Keisuke, Takami, Shinichiro, Shimodaira, Shigetaka, Okamoto, Masato, Ohkusa, Toshifumi, Koido, Shigeo
Publié dans World J Gastroenterol (2016)

Regulation of Tumor Immunity by Tumor/Dendritic Cell Fusions

par Koido, Shigeo, Homma, Sadamu, Hara, Eiichi, Namiki, Yoshihisa, Takahara, Akitaka, Komita, Hideo, Nagasaki, Eijiro, Ito, Masaki, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao
Publié 2010

Clinical significance of serum procalcitonin in patients with ulcerative colitis

par Koido, Shigeo, Ohkusa, Toshifumi, Takakura, Kazuki, Odahara, Shunichi, Tsukinaga, Shintaro, Yukawa, Toyokazu, Mitobe, Jimi, Kajihara, Mikio, Uchiyama, Kan, Arakawa, Hiroshi, Tajiri, Hisao
Publié 2013

Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model

par Takakura, Kazuki, Shibazaki, Yuichiro, Yoneyama, Hiroyuki, Fujii, Masato, Hashiguchi, Taishi, Ito, Zensho, Kajihara, Mikio, Misawa, Takeyuki, Homma, Sadamu, Ohkusa, Toshifumi, Koido, Shigeo
Publié dans PLoS One (2015)

Impact of maternal dietary gut microbial metabolites on an offspring’s systemic immune response in mouse models

par NAKAJIMA, Akihito, HABU, Sonoko, KASAI, Masataka, OKUMURA, Ko, ISHIKAWA, Dai, SHIBUYA, Tomoyoshi, KOBAYASHI, Osamu, OSADA, Taro, OHKUSA, Toshifumi, WATANABE, Sumio, NAGAHARA, Akihito
Publié dans Biosci Microbiota Food Health (2020)

High‐dose linaclotide is effective and safe in patients with chronic constipation: A phase III randomized, double‐blind, placebo‐controlled study with a long‐term open‐label extens...

par Fukudo, Shin, Miwa, Hiroto, Nakajima, Atsushi, Kinoshita, Yoshikazu, Kosako, Masanori, Hayashi, Kenta, Akiho, Hiraku, Kuroishi, Kentaro, Johnston, Jeffrey M, Currie, Mark, Ohkusa, Toshifumi
Publié dans Neurogastroenterol Motil (2018)

Improved immunogenicity of fusions between ethanol-treated cancer cells and dendritic cells exposed to dual TLR stimulation

par Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Namiki, Yoshihisa, Kan, Shin, Takakura, Kazuki, Kajihara, Mikio, Uchiyama, Kan, Hara, Eiich, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao
Publié 2013