A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Azathioprine (AZA) is frequently used in patients with inflammatory bowel disease (IBD). However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the precise mechanisms underlying thiopurine-related toxicity are not well understood. To investigate the relations...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Odahara, Shunichi, Uchiyama, Kan, Kubota, Takahiro, Ito, Zensho, Takami, Shinichiro, Kobayashi, Hiroko, Saito, Keisuke, Koido, Shigeo, Ohkusa, Toshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567281/
https://ncbi.nlm.nih.gov/pubmed/26360046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137798
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