A Prospective Study Evaluating Metabolic Capacity of Thiopurine and Associated Adverse Reactions in Japanese Patients with Inflammatory Bowel Disease (IBD)

Azathioprine (AZA) is frequently used in patients with inflammatory bowel disease (IBD). However, toxic adverse reactions frequently develop and limit the clinical benefits. Currently, the precise mechanisms underlying thiopurine-related toxicity are not well understood. To investigate the relations...

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Vydáno v:PLoS One
Hlavní autoři: Odahara, Shunichi, Uchiyama, Kan, Kubota, Takahiro, Ito, Zensho, Takami, Shinichiro, Kobayashi, Hiroko, Saito, Keisuke, Koido, Shigeo, Ohkusa, Toshifumi
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4567281/
https://ncbi.nlm.nih.gov/pubmed/26360046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137798
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