Improved immunogenicity of fusions between ethanol-treated cancer cells and dendritic cells exposed to dual TLR stimulation

Tumor-derived transforming growth factor β1 (TGFβ1) generally abrogates the immunogenicity of dendritic cells (DCs) fused to whole cancer cells. We have recently revealed that ethanol-treated neoplastic cells fused to DCs exposed to 2 Toll-like receptor agonists efficiently induce cytotoxic T lympho...

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Main Authors: Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Namiki, Yoshihisa, Kan, Shin, Takakura, Kazuki, Kajihara, Mikio, Uchiyama, Kan, Hara, Eiich, Ohkusa, Toshifumi, Gong, Jianlin, Tajiri, Hisao
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2013
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805650/
https://ncbi.nlm.nih.gov/pubmed/24167764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25375
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