Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model

Chondroitin sulfate E (CS-E), a highly sulfated glycosaminoglycan, is known to promote tumor invasion and metastasis. Because the presence of CS-E is detected in both tumor and stromal cells in pancreatic ductal adenocarcinoma (PDAC), multistage involvement of CS-E in the development of PDAC has bee...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Takakura, Kazuki, Shibazaki, Yuichiro, Yoneyama, Hiroyuki, Fujii, Masato, Hashiguchi, Taishi, Ito, Zensho, Kajihara, Mikio, Misawa, Takeyuki, Homma, Sadamu, Ohkusa, Toshifumi, Koido, Shigeo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4671730/
https://ncbi.nlm.nih.gov/pubmed/26642349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142981
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