Chemoimmunotherapy targeting Wilms’ tumor 1 (WT1)-specific cytotoxic T lymphocyte and helper T cell responses for patients with pancreatic cancer

We designed a phase 1 study using dendritic cells (DCs) pulsed with a mixture of three types of Wilms’ tumor 1 (WT1) peptides, including MHC class I/II restricted epitopes (DC/WT1-I/II). Our recent work reveals that the combination of DC/WT1-I/II and chemotherapy induced long-term WT1-specific CD4(+...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Koido, Shigeo, Homma, Sadamu, Okamoto, Masato, Takakura, Kazuki, Gong, Jianlin, Sugiyama, Haruo, Ohkusa, Toshifumi, Tajiri, Hisao
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292571/
https://ncbi.nlm.nih.gov/pubmed/25941581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.958950
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