Diabetic painful and insensate neuropathy: Pathogenesis and potential treatments

Por Obrosova, Irina G.
Publicado no Neurotherapeutics (2009)

POLY(ADP-RIBOSE) POLYMERASE-1 (PARP-1) GENE DEFICIENCY ALLEVIATES DIABETIC KIDNEY DISEASE

Por Shevalye, Hanna, Maksimchyk, Yury, Watcho, Pierre, Obrosova, Irina G.
Publicado em 2010

Role of Nitrosative Stress and Peroxynitrite in the Pathogenesis of Diabetic Complications. Emerging New Therapeutical Strategies

Por Pacher, Pál, Obrosova, Irina G., Mabley, Jon G., Szabó, Csaba
Publicado em 2005

Aldose reductase inhibition counteracts nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic rat kidney and high-glucose-exposed human mesangial cells

Por Drel, Viktor R., Pacher, Pal, Stevens, Martin J., Obrosova, Irina G.
Publicado em 2006

Endoplasmic Reticulum Stress Plays a Key Role in the Pathogenesis of Diabetic Peripheral Neuropathy

Por Lupachyk, Sergey, Watcho, Pierre, Stavniichuk, Roman, Shevalye, Hanna, Obrosova, Irina G.
Publicado em 2013

High-Fat Diet-Induced Neuropathy of Prediabetes and Obesity: Effect of PMI-5011, an Ethanolic Extract of Artemisia dracunculus L.

Por Watcho, Pierre, Stavniichuk, Roman, Ribnicky, David M., Raskin, Ilya, Obrosova, Irina G.
Publicado em 2010

PARP INHIBITION ALLEVIATES DIABETES-INDUCED SYSTEMIC OXIDATIVE STRESS AND NEURAL TISSUE 4-HYDROXYNONENAL ADDUCT ACCUMULATION: CORRELATION WITH PERIPHERAL NERVE FUNCTION

Por Lupachyk, Sergey, Shevalye, Hanna, Maksimchyk, Yury, Drel, Viktor R., Obrosova, Irina G.
Publicado em 2011

INTERPLAY OF SORBITOL PATHWAY OF GLUCOSE METABOLISM, 12/15-LIPOXYGENASE, AND MITOGEN-ACTIVATED PROTEIN KINASES IN THE PATHOGENESIS OF DIABETIC PERIPHERAL NEUROPATHY

Por Stavniichuk, Roman, Shevalye, Hanna, Hirooka, Hiroko, Nadler, Jerry L., Obrosova, Irina G.
Publicado em 2012

Peripheral neuropathy in mice with neuronal nitric oxide synthase gene deficiency

Por VARENIUK, IGOR, PACHER, PAL, PAVLOV, IVAN A., DREL, VIKTOR R., OBROSOVA, IRINA G.
Publicado em 2009

Metanx Alleviates Multiple Manifestations of Peripheral Neuropathy and Increases Intraepidermal Nerve Fiber Density in Zucker Diabetic Fatty Rats

Por Shevalye, Hanna, Watcho, Pierre, Stavniichuk, Roman, Dyukova, Elena, Lupachyk, Sergey, Obrosova, Irina G.
Publicado em 2012

Evaluation of PMI-5011, an ethanolic extract of Artemisia dracunculus L., on peripheral neuropathy in streptozotocin-diabetic mice

Por WATCHO, PIERRE, STAVNIICHUK, ROMAN, TANE, PIERRE, SHEVALYE, HANNA, MAKSIMCHYK, YURY, PACHER, PAL, OBROSOVA, IRINA G.
Publicado em 2011

Prediabetic Nephropathy as an Early Consequence of the High-Calorie/High-Fat Diet: Relation to Oxidative Stress

Por Shevalye, Hanna, Lupachyk, Sergey, Watcho, Pierre, Stavniichuk, Roman, Khazim, Khaled, Abboud, Hanna E., Obrosova, Irina G.
Publicado em 2012

Na(+)/H(+) exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats

Por Lupachyk, Sergey, Watcho, Pierre, Shevalye, Hanna, Vareniuk, Igor, Obrosov, Alexander, Obrosova, Irina G., Yorek, Mark A.
Publicado em 2013

Peroxynitrite and Protein Nitration in the Pathogenesis of Diabetic Peripheral Neuropathy

Por Stavniichuk, Roman, Shevalye, Hanna, Lupachyk, Sergey, Obrosov, Alexander, Groves, John T., Obrosova, Irina G., Yorek, Mark A.
Publicado em 2014

Aldose Reductase Inhibition Counteracts Oxidative-Nitrosative Stress and Poly(ADP-Ribose) Polymerase Activation in Tissue Sites for Diabetes Complications

Por Obrosova, Irina G., Pacher, Pal, Szabó, Csaba, Zsengeller, Zsuzsanna, Hirooka, Hiroko, Stevens, Martin J., Yorek, Mark A.
Publicado em 2005

Poly(Adenosine 5′-Diphosphate-Ribose) Polymerase Inhibition Counteracts Multiple Manifestations of Experimental Type 1 Diabetic Nephropathy

Por Drel, Viktor R., Xu, Weizheng, Zhang, Jie, Pavlov, Ivan A., Shevalye, Hanna, Slusher, Barbara, Obrosova, Irina G.
Publicado em 2009

12/15-Lipoxygenase inhibition counteracts MAPK phosphorylation in mouse and cell culture models of diabetic peripheral neuropathy

Por Stavniichuk, Roman, Obrosov, Alexander A., Drel, Viktor R., Nadler, Jerry L., Obrosova, Irina G., Yorek, Mark A.
Publicado em 2013

Role of Peroxynitrite in the Development of Diabetic Peripheral Neuropathy

Por Edwards, Joshua F., Casellini, Carolina M., Parson, Henri K., Obrosova, Irina G., Yorek, Mark, Vinik, Aaron I.
Publicado no Diabetes Care (2015)

Cannabidiol attenuates high glucose-induced endothelial cell inflammatory response and barrier disruption

Por Rajesh, Mohanraj, Mukhopadhyay, Partha, Bátkai, Sándor, Haskó, György, Liaudet, Lucas, Drel, Viktor R., Obrosova, Irina G., Pacher, Pál
Publicado em 2007

Different Roles of 12/15-Lipoxygenase in Diabetic Large and Small Fiber Peripheral and Autonomic Neuropathies

Por Obrosova, Irina G., Stavniichuk, Roman, Drel, Viktor R., Shevalye, Hanna, Vareniuk, Igor, Nadler, Jerry L., Schmidt, Robert. E.
Publicado em 2010