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Peroxynitrite and Protein Nitration in the Pathogenesis of Diabetic Peripheral Neuropathy

Peroxynitrite, a product of the reaction of superoxide with nitric oxide, causes oxidative stress with concomitant inactivation of enzymes, poly(ADP-ribosylation), mitochondrial dysfunction, impaired stress signaling, as well as protein nitration. In this study we sought to determine the effect of p...

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Detalhes bibliográficos
Main Authors: Stavniichuk, Roman, Shevalye, Hanna, Lupachyk, Sergey, Obrosov, Alexander, Groves, John T., Obrosova, Irina G., Yorek, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4177961/
https://ncbi.nlm.nih.gov/pubmed/24687457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dmrr.2549
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