Stop relaxing: How DNA damage-induced chromatin compaction may affect epigenetic integrity and disease

Por Oberdoerffer, Philipp
Publicado no Mol Cell Oncol (2014)

The ageing epigenome: damaged beyond repair?

Por Sinclair, David, Oberdoerffer, Philipp
Publicado em 2009

Chromatin dynamics in DNA double-strand break repair

Por Shi, Lei, Oberdoerffer, Philipp
Publicado em 2012

Replication Stress: A Lifetime of Epigenetic Change

Por Khurana, Simran, Oberdoerffer, Philipp
Publicado no Genes (Basel) (2015)

Transcription-associated events affecting genomic integrity

Por Sebastian, Robin, Oberdoerffer, Philipp
Publicado no Philos Trans R Soc Lond B Biol Sci (2017)

Metabolic modulation of chromatin: implications for DNA repair and genomic integrity

Por Liu, Jinping, Kim, Jeongkyu, Oberdoerffer, Philipp
Publicado em 2013

The histone variant macroH2A1 is a splicing-modulated caretaker of genome integrity and tumor growth

Por Kim, Jeongkyu, Oberdoerffer, Philipp, Khurana, Simran
Publicado no Mol Cell Oncol (2018)

Expression of a Targeted λ1 Light Chain Gene Is Developmentally Regulated and Independent of Igκ Rearrangements

Por Oberdoerffer, Philipp, Novobrantseva, Tatiana I., Rajewsky, Klaus
Publicado em 2003

DNA damage, chromatin, and transcription: the trinity of aging

Por Burgess, Rebecca C., Misteli, Tom, Oberdoerffer, Philipp
Publicado em 2012

Unidirectional Cre-mediated genetic inversion in mice using the mutant loxP pair lox66/lox71

Por Oberdoerffer, Philipp, Otipoby, Kevin L., Maruyama, Mitsuo, Rajewsky, Klaus
Publicado em 2003

Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability

Por Kim, Jeongkyu, Sturgill, David, Tran, Andy D., Sinclair, David A., Oberdoerffer, Philipp
Publicado no Nucleic Acids Res (2016)

A BRCA1-interacting lncRNA regulates homologous recombination

Por Sharma, Vivek, Khurana, Simran, Kubben, Nard, Abdelmohsen, Kotb, Oberdoerffer, Philipp, Gorospe, Myriam, Misteli, Tom
Publicado no EMBO Rep (2015)

Sirt1 ablation promotes stress-induced loss of epigenetic and genomic hematopoietic stem and progenitor cell maintenance

Por Singh, Satyendra K., Williams, Carrie A., Klarmann, Kimberly, Burkett, Sandra S., Keller, Jonathan R., Oberdoerffer, Philipp
Publicado em 2013

Efficiency of RNA Interference in the Mouse Hematopoietic System Varies between Cell Types and Developmental Stages

Por Oberdoerffer, Philipp, Kanellopoulou, Chryssa, Heissmeyer, Vigo, Paeper, Corinna, Borowski, Christine, Aifantis, Iannis, Rao, Anjana, Rajewsky, Klaus
Publicado em 2005

Ubiquitin-specific protease 21 stabilizes BRCA2 to control DNA repair and tumor growth

Por Liu, Jinping, Kruswick, Alex, Dang, Hien, Tran, Andy D., Kwon, So Mee, Wang, Xin Wei, Oberdoerffer, Philipp
Publicado no Nat Commun (2017)

A Macrohistone Variant Links Dynamic Chromatin Compaction to BRCA1-Dependent Genome Maintenance

Por Khurana, Simran, Kruhlak, Michael J., Kim, Jeongkyu, Tran, Andy D., Liu, Jinping, Nyswaner, Katherine, Shi, Lei, Jailwala, Parthav, Sung, Myong-Hee, Hakim, Ofir, Oberdoerffer, Philipp
Publicado em 2014

The SIRT1 Deacetylase Suppresses Intestinal Tumorigenesis and Colon Cancer Growth

Por Firestein, Ron, Blander, Gil, Michan, Shaday, Oberdoerffer, Philipp, Ogino, Shuji, Campbell, Jennifer, Bhimavarapu, Anupama, Luikenhuis, Sandra, de Cabo, Rafael, Fuchs, Charles, Hahn, William C., Guarente, Leonard P., Sinclair, David A.
Publicado em 2008

Replication stress shapes a protective chromatin environment across fragile genomic regions

Por Kim, Jeongkyu, Sturgill, David, Sebastian, Robin, Khurana, Simran, Tran, Andy D., Edwards, Garrett B., Kruswick, Alex, Burkett, Sandra, Hosogane, Eri K., Hannon, William W., Weyemi, Urbain, Bonner, William M., Luger, Karolin, Oberdoerffer, Philipp
Publicado no Mol Cell (2017)

The BCL2A1 gene as a pre–T cell receptor–induced regulator of thymocyte survival

Por Mandal, Malay, Borowski, Christine, Palomero, Teresa, Ferrando, Adolfo A., Oberdoerffer, Philipp, Meng, Fanyong, Ruiz-Vela, Antonio, Ciofani, Maria, Zuniga-Pflucker, Juan-Carlos, Screpanti, Isabella, Look, A. Thomas, Korsmeyer, Stanley J., Rajewsky, Klaus, von Boehmer, Harald, Aifantis, Iannis
Publicado em 2005

DNA damage-induced alterations in chromatin contribute to genomic integrity and age-related changes in gene expression

Por Oberdoerffer, Philipp, Michan, Shaday, McVay, Michael, Mostoslavsky, Raul, Vann, James, Park, Sang-Kyu, Hartlerode, Andrea, Stegmuller, Judith, Hafner, Angela, Loerch, Patrick, Wright, Sarah M., Mills, Kevin D., Bonni, Azad, Yankner, Bruce A., Scully, Ralph, Prolla, Tomas A., Alt, Frederick W., Sinclair, David A.
Publicado em 2008