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Stop relaxing: How DNA damage-induced chromatin compaction may affect epigenetic integrity and disease

DNA damage is widely recognized for its potential to impair epigenetic integrity. Epigenetic defects are closely associated with a variety of diseases. We have recently uncovered DNA double-strand break-induced chromatin condensation as a critical modulator of repair outcome. Here, we discuss the po...

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Bibliografske podrobnosti
izdano v:Mol Cell Oncol
Glavni avtor: Oberdoerffer, Philipp
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905243/
https://ncbi.nlm.nih.gov/pubmed/27308388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.970952
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