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Global chromatin compaction limits the strength of the DNA damage response

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA damage response (DDR) has not directly been tested and thus remains speculative. We apply two independ...

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Main Authors: Murga, Matilde, Jaco, Isabel, Fan, Yuhong, Soria, Rebeca, Martinez-Pastor, Barbara, Cuadrado, Myriam, Yang, Seung-Min, Blasco, Maria A., Skoultchi, Arthur I., Fernandez-Capetillo, Oscar
פורמט: Artigo
שפה:Inglês
יצא לאור: The Rockefeller University Press 2007
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064646/
https://ncbi.nlm.nih.gov/pubmed/17893239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704140
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