Global chromatin compaction limits the strength of the DNA damage response

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA damage response (DDR) has not directly been tested and thus remains speculative. We apply two independ...

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Detalhes bibliográficos
Main Authors: Murga, Matilde, Jaco, Isabel, Fan, Yuhong, Soria, Rebeca, Martinez-Pastor, Barbara, Cuadrado, Myriam, Yang, Seung-Min, Blasco, Maria A., Skoultchi, Arthur I., Fernandez-Capetillo, Oscar
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064646/
https://ncbi.nlm.nih.gov/pubmed/17893239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704140
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