Global chromatin compaction limits the strength of the DNA damage response

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA damage response (DDR) has not directly been tested and thus remains speculative. We apply two independ...

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Bibliografiske detaljer
Main Authors: Murga, Matilde, Jaco, Isabel, Fan, Yuhong, Soria, Rebeca, Martinez-Pastor, Barbara, Cuadrado, Myriam, Yang, Seung-Min, Blasco, Maria A., Skoultchi, Arthur I., Fernandez-Capetillo, Oscar
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2007
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064646/
https://ncbi.nlm.nih.gov/pubmed/17893239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704140
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