Global chromatin compaction limits the strength of the DNA damage response

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA damage response (DDR) has not directly been tested and thus remains speculative. We apply two independ...

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Autores principales: Murga, Matilde, Jaco, Isabel, Fan, Yuhong, Soria, Rebeca, Martinez-Pastor, Barbara, Cuadrado, Myriam, Yang, Seung-Min, Blasco, Maria A., Skoultchi, Arthur I., Fernandez-Capetillo, Oscar
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2007
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064646/
https://ncbi.nlm.nih.gov/pubmed/17893239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704140
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