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Global chromatin compaction limits the strength of the DNA damage response

In response to DNA damage, chromatin undergoes a global decondensation process that has been proposed to facilitate genome surveillance. However, the impact that chromatin compaction has on the DNA damage response (DDR) has not directly been tested and thus remains speculative. We apply two independ...

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Bibliografski detalji
Glavni autori: Murga, Matilde, Jaco, Isabel, Fan, Yuhong, Soria, Rebeca, Martinez-Pastor, Barbara, Cuadrado, Myriam, Yang, Seung-Min, Blasco, Maria A., Skoultchi, Arthur I., Fernandez-Capetillo, Oscar
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064646/
https://ncbi.nlm.nih.gov/pubmed/17893239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200704140
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