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Controlled DNA double-strand break induction in mice reveals post-damage transcriptome stability
DNA double-strand breaks (DSBs) and their repair can cause extensive epigenetic changes. As a result, DSBs have been proposed to promote transcriptional and, ultimately, physiological dysfunction via both cell-intrinsic and cell-non-autonomous pathways. Studying the consequences of DSBs in higher or...
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Publicado no: | Nucleic Acids Res |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4838352/ https://ncbi.nlm.nih.gov/pubmed/26687720 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1482 |
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