A Chemical View of Oligonucleotides for Exon Skipping and Related Drug Applications

Por Järver, Peter, O'Donovan, Liz, Gait, Michael J.
Publicado em 2014

Parallel Synthesis of Cell-Penetrating Peptide Conjugates of PMO Toward Exon Skipping Enhancement in Duchenne Muscular Dystrophy

Por O'Donovan, Liz, Okamoto, Itaru, Arzumanov, Andrey A., Williams, Donna L., Deuss, Peter, Gait, Michael J.
Publicado no Nucleic Acid Ther (2015)

Development and Application of an Ultrasensitive Hybridization-Based ELISA Method for the Determination of Peptide-Conjugated Phosphorodiamidate Morpholino Oligonucleotides

Por Burki, Umar, Keane, Jonathan, Blain, Alison, O'Donovan, Liz, Gait, Michael John, Laval, Steven H., Straub, Volker
Publicado no Nucleic Acid Ther (2015)

Delivery of therapeutic oligonucleotides with cell penetrating peptides()

Por Boisguérin, Prisca, Deshayes, Sébastien, Gait, Michael J., O'Donovan, Liz, Godfrey, Caroline, Betts, Corinne A., Wood, Matthew J.A., Lebleu, Bernard
Publicado no Adv Drug Deliv Rev (2015)

Peptide-conjugated phosphodiamidate oligomer-mediated exon skipping has benefits for cardiac function in mdx and Cmah-/-mdx mouse models of Duchenne muscular dystrophy

Por Blain, Alison M., Greally, Elizabeth, McClorey, Graham, Manzano, Raquel, Betts, Corinne A., Godfrey, Caroline, O’Donovan, Liz, Coursindel, Thibault, Gait, Mike J., Wood, Matthew J., MacGowan, Guy A., Straub, Volker W.
Publicado no PLoS One (2018)

How much dystrophin is enough: the physiological consequences of different levels of dystrophin in the mdx mouse

Por Godfrey, Caroline, Muses, Sofia, McClorey, Graham, Wells, Kim E., Coursindel, Thibault, Terry, Rebecca L., Betts, Corinne, Hammond, Suzan, O'Donovan, Liz, Hildyard, John, El Andaloussi, Samir, Gait, Michael J., Wood, Matthew J., Wells, Dominic J.
Publicado no Hum Mol Genet (2015)

Comprehensive RNA-Sequencing Analysis in Serum and Muscle Reveals Novel Small RNA Signatures with Biomarker Potential for DMD

Por Coenen-Stass, Anna M.L., Sork, Helena, Gatto, Sole, Godfrey, Caroline, Bhomra, Amarjit, Krjutškov, Kaarel, Hart, Jonathan R., Westholm, Jakub O., O’Donovan, Liz, Roos, Andreas, Lochmüller, Hanns, Puri, Pier Lorenzo, EL Andaloussi, Samir, Wood, Matthew J.A., Roberts, Thomas C.
Publicado no Mol Ther Nucleic Acids (2018)

Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment

Por Betts, Corinne A, McClorey, Graham, Healicon, Richard, Hammond, Suzan M, Manzano, Raquel, Muses, Sofia, Ball, Vicky, Godfrey, Caroline, Merritt, Thomas M, van Westering, Tirsa, O’Donovan, Liz, Wells, Kim E, Gait, Michael J, Wells, Dominic J, Tyler, Damian, Wood, Matthew J
Publicado no Hum Mol Genet (2019)

Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides

Por Ezzat, Kariem, Aoki, Yoshitsugu, Koo, Taeyoung, McClorey, Graham, Benner, Leif, Coenen-Stass, Anna, O'Donovan, Liz, Lehto, Taavi, Garcia-Guerra, Antonio, Nordin, Joel, Saleh, Amer F., Behlke, Mark, Morris, John, Goyenvalle, Aurelie, Dugovic, Branislav, Leumann, Christian, Gordon, Siamon, Gait, Michael J., El–Andaloussi, Samir, Wood, Matthew JA
Publicado no Nano Lett (2015)