Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment

Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by progressive dilated cardiomyopathy, decreased fractional shortening and metab...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Hum Mol Genet
Main Authors: Betts, Corinne A, McClorey, Graham, Healicon, Richard, Hammond, Suzan M, Manzano, Raquel, Muses, Sofia, Ball, Vicky, Godfrey, Caroline, Merritt, Thomas M, van Westering, Tirsa, O’Donovan, Liz, Wells, Kim E, Gait, Michael J, Wells, Dominic J, Tyler, Damian, Wood, Matthew J
פורמט: Artigo
שפה:Inglês
יצא לאור: Oxford University Press 2019
נושאים:
General Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337703/
https://ncbi.nlm.nih.gov/pubmed/30281092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy346
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים