Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment

Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by progressive dilated cardiomyopathy, decreased fractional shortening and metab...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Hum Mol Genet
Main Authors: Betts, Corinne A, McClorey, Graham, Healicon, Richard, Hammond, Suzan M, Manzano, Raquel, Muses, Sofia, Ball, Vicky, Godfrey, Caroline, Merritt, Thomas M, van Westering, Tirsa, O’Donovan, Liz, Wells, Kim E, Gait, Michael J, Wells, Dominic J, Tyler, Damian, Wood, Matthew J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
General Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337703/
https://ncbi.nlm.nih.gov/pubmed/30281092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy346
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares