Cmah-dystrophin deficient mdx mice display an accelerated cardiac phenotype that is improved following peptide-PMO exon skipping treatment

Duchenne muscular dystrophy (DMD) is caused by loss of dystrophin protein, leading to progressive muscle weakness and premature death due to respiratory and/or cardiac complications. Cardiac involvement is characterized by progressive dilated cardiomyopathy, decreased fractional shortening and metab...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Hum Mol Genet
मुख्य लेखकों: Betts, Corinne A, McClorey, Graham, Healicon, Richard, Hammond, Suzan M, Manzano, Raquel, Muses, Sofia, Ball, Vicky, Godfrey, Caroline, Merritt, Thomas M, van Westering, Tirsa, O’Donovan, Liz, Wells, Kim E, Gait, Michael J, Wells, Dominic J, Tyler, Damian, Wood, Matthew J
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2019
विषय:
General Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6337703/
https://ncbi.nlm.nih.gov/pubmed/30281092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddy346
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