Re-evaluation of the Mutagenic Response to Phosphorothioate Nucleotides in Human Lymphoblastoid TK6 Cells

по Saleh, Amer F., Priestley, Catherine C., Gooderham, Nigel J., Fellows, Mick D.
Опубликовано в: Toxicol Sci (2015)

Synthesis and Splice-Redirecting Activity of Branched, Arginine-Rich Peptide Dendrimer Conjugates of Peptide Nucleic Acid Oligonucleotides

по Saleh, Amer F., Arzumanov, Andrey, Abes, Rachida, Owen, David, Lebleu, Bernard, Gait, Michael J.
Опубликовано 2010

Bi-specific splice-switching PMO oligonucleotides conjugated via a single peptide active in a mouse model of Duchenne muscular dystrophy

по Shabanpoor, Fazel, McClorey, Graham, Saleh, Amer F., Järver, Peter, Wood, Matthew J.A., Gait, Michael J.
Опубликовано в: Nucleic Acids Res (2015)

Combination Antisense Treatment for Destructive Exon Skipping of Myostatin and Open Reading Frame Rescue of Dystrophin in Neonatal mdx Mice

по Lu-Nguyen, Ngoc B, Jarmin, Susan A, Saleh, Amer F, Popplewell, Linda, Gait, Michael J, Dickson, George
Опубликовано в: Mol Ther (2015)

Pip6-PMO, A New Generation of Peptide-oligonucleotide Conjugates With Improved Cardiac Exon Skipping Activity for DMD Treatment

по Betts, Corinne, Saleh, Amer F, Arzumanov, Andrey A, Hammond, Suzan M, Godfrey, Caroline, Coursindel, Thibault, Gait, Michael J, Wood, Matthew JA
Опубликовано 2012

Dual Myostatin and Dystrophin Exon Skipping by Morpholino Nucleic Acid Oligomers Conjugated to a Cell-penetrating Peptide Is a Promising Therapeutic Strategy for the Treatment of D...

по Malerba, Alberto, Kang, Jagjeet K, McClorey, Graham, Saleh, Amer F, Popplewell, Linda, Gait, Michael J, Wood, Matthew JA, Dickson, George
Опубликовано 2012

Optimization of Peptide Nucleic Acid Antisense Oligonucleotides for Local and Systemic Dystrophin Splice Correction in the mdx Mouse

по Yin, HaiFang, Betts, Corinne, Saleh, Amer F, Ivanova, Gabriela D, Lee, Hyunil, Seow, Yiqi, Kim, Dalsoo, Gait, Michael J, Wood, Matthew JA
Опубликовано 2010

Selection of Fluorescent, Bioluminescent, and Radioactive Tracers to Accurately Reflect Extracellular Vesicle Biodistribution in Vivo

по Lázaro-Ibáñez, Elisa, Faruqu, Farid N., Saleh, Amer F., Silva, Andreia M., Tzu-Wen Wang, Julie, Rak, Janusz, Al-Jamal, Khuloud T., Dekker, Niek
Опубликовано в: ACS Nano (2021)

Pip5 Transduction Peptides Direct High Efficiency Oligonucleotide-mediated Dystrophin Exon Skipping in Heart and Phenotypic Correction in mdx Mice

по Yin, HaiFang, Saleh, Amer F, Betts, Corinne, Camelliti, Patrizia, Seow, Yiqi, Ashraf, Shirin, Arzumanov, Andrey, Hammond, Suzan, Merritt, Thomas, Gait, Michael J, Wood, Matthew JA
Опубликовано 2011

Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics

по Coenen-Stass, Anna M. L., McClorey, Graham, Manzano, Raquel, Betts, Corinne A., Blain, Alison, Saleh, Amer F., Gait, Michael J., Lochmüller, Hanns, Wood, Matthew J. A., Roberts, Thomas C.
Опубликовано в: Sci Rep (2015)

Corrigendum: Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics

по Coenen-Stass, Anna M. L., McClorey, Graham, Manzano, Raquel, Betts, Corinne A., Blain, Alison, Saleh, Amer F., Gait, Michael J., Lochmüller, Hanns, Wood, Matthew J. A., Roberts, Thomas C.
Опубликовано в: Sci Rep (2016)

Systemic peptide-mediated oligonucleotide therapy improves long-term survival in spinal muscular atrophy

по Hammond, Suzan M., Hazell, Gareth, Shabanpoor, Fazel, Saleh, Amer F., Bowerman, Melissa, Sleigh, James N., Meijboom, Katharina E., Zhou, Haiyan, Muntoni, Francesco, Talbot, Kevin, Gait, Michael J., Wood, Matthew J. A.
Опубликовано в: Proc Natl Acad Sci U S A (2016)

Peptide Nanoparticle Delivery of Charge-Neutral Splice-Switching Morpholino Oligonucleotides

по Järver, Peter, Zaghloul, Eman M., Arzumanov, Andrey A., Saleh, Amer F., McClorey, Graham, Hammond, Suzan M., Hällbrink, Mattias, Langel, Ülo, Smith, C.I. Edvard, Wood, Matthew J.A., Gait, Michael J., EL Andaloussi, Samir
Опубликовано в: Nucleic Acid Ther (2015)

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy

по Betts, Corinne A., Saleh, Amer F., Carr, Carolyn A., Muses, Sofia, Wells, Kim E., Hammond, Suzan M., Godfrey, Caroline, McClorey, Graham, Woffindale, Caroline, Clarke, Kieran, Wells, Dominic J., Gait, Michael J., Wood, Matthew J. A.
Опубликовано в: Sci Rep (2015)

Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice

по Betts, Corinne A., Saleh, Amer F., Carr, Carolyn A., Hammond, Suzan M., Coenen-Stass, Anna M. L., Godfrey, Caroline, McClorey, Graham, Varela, Miguel A., Roberts, Thomas C., Clarke, Kieran, Gait, Michael J., Wood, Matthew J. A.
Опубликовано в: Sci Rep (2015)

Self-assembly into nanoparticles is essential for receptor mediated uptake of therapeutic antisense oligonucleotides

по Ezzat, Kariem, Aoki, Yoshitsugu, Koo, Taeyoung, McClorey, Graham, Benner, Leif, Coenen-Stass, Anna, O'Donovan, Liz, Lehto, Taavi, Garcia-Guerra, Antonio, Nordin, Joel, Saleh, Amer F., Behlke, Mark, Morris, John, Goyenvalle, Aurelie, Dugovic, Branislav, Leumann, Christian, Gordon, Siamon, Gait, Michael J., El–Andaloussi, Samir, Wood, Matthew JA
Опубликовано в: Nano Lett (2015)

Splice-correcting oligonucleotides restore BTK function in X-linked agammaglobulinemia model

по Bestas, Burcu, Moreno, Pedro M.D., Blomberg, K. Emelie M., Mohammad, Dara K., Saleh, Amer F., Sutlu, Tolga, Nordin, Joel Z., Guterstam, Peter, Gustafsson, Manuela O., Kharazi, Shabnam, Piątosa, Barbara, Roberts, Thomas C., Behlke, Mark A., Wood, Matthew J.A., Gait, Michael J., Lundin, Karin E., El Andaloussi, Samir, Månsson, Robert, Berglöf, Anna, Wengel, Jesper, Smith, C.I. Edvard
Опубликовано 2014