AdmixKJump: identifying population structure in recently diverged groups

par O’Connor, Timothy D
Publié dans Source Code Biol Med (2015)

Genotype–phenotype associations: substitution models to detect evolutionary associations between phenotypic variables and genotypic evolutionary rate

par O'Connor, Timothy D., Mundy, Nicholas I.
Publié 2009

Evolutionary Modeling of Genotype-Phenotype Associations, and Application to Primate Coding and Non-coding mtDNA Rate Variation

par O’Connor, Timothy D., Mundy, Nicholas I.
Publié 2013

Accurate and equitable medical genomic analysis requires an understanding of demography and its influence on sample size and ratio

par Kessler, Michael D., O’Connor, Timothy D.
Publié dans Genome Biol (2017)

Genetic architecture of quantitative traits and complex diseases

par Fu, Wenqing, O’Connor, Timothy D., Akey, Joshua M.
Publié dans Curr Opin Genet Dev (2013)

Inferring the “Primordial Immune Complex”: Origins of MHC class I and antigen receptors revealed by comparative genomics

par Ohta, Yuko, Kasahara, Masanori, O’Connor, Timothy D., Flajnik, Martin F.
Publié dans J Immunol (2019)

The promise and limitations of population exomics for human evolution studies

par Tennessen, Jacob A, O'Connor, Timothy D, Bamshad, Michael J, Akey, Joshua M
Publié 2011

Improving Cancer Detection and Treatment with Liquid Biopsies and ptDNA

par Kessler, Michael D., Pawar, Nisha R., Martin, Stuart S, Antalis, Toni M., O’Connor, Timothy D.
Publié dans Trends Cancer (2018)

Ancestral characterization of 1018 cancer cell lines highlights disparities and reveals gene expression and mutational differences

par Kessler, Michael D., Bateman, Nicholas W., Conrads, Thomas P., Maxwell, George L., Dunning Hotopp, Julie C., O’Connor, Timothy D.
Publié dans Cancer (2019)

Fine-Scale Patterns of Population Stratification Confound Rare Variant Association Tests

par O’Connor, Timothy D., Kiezun, Adam, Bamshad, Michael, Rich, Stephen S., Smith, Joshua D., Turner, Emily, Leal, Suzanne M., Akey, Joshua M.
Publié 2013

Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World

par Harris, Daniel N, Ruczinski, Ingo, Yanek, Lisa R, Becker, Lewis C, Becker, Diane M, Guio, Heinner, Cui, Tao, Chilton, Floyd H, Mathias, Rasika A, O’Connor, Timothy D
Publié dans Genome Biol Evol (2019)

Using genotype array data to compare multi- and single-sample variant calls and improve variant call sets from deep coverage whole-genome sequencing data

par Shringarpure, Suyash S, Mathias, Rasika A, Hernandez, Ryan D, O’Connor, Timothy D, Szpiech, Zachary A, Torres, Raul, De La Vega, Francisco M, Bustamante, Carlos D, Barnes, Kathleen C, Taub, Margaret A
Publié dans Bioinformatics (2017)

Rare Variation Facilitates Inferences of Fine-Scale Population Structure in Humans

par O’Connor, Timothy D., Fu, Wenqing, Mychaleckyj, Josyf C., Logsdon, Benjamin, Auer, Paul, Carlson, Christopher S., Leal, Suzanne M., Smith, Joshua D., Rieder, Mark J., Bamshad, Michael J., Nickerson, Deborah A., Akey, Joshua M.
Publié dans Mol Biol Evol (2015)

Analysis of 6,515 exomes reveals a recent origin of most human protein-coding variants

par Fu, Wenqing, O'Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., GO, Broad, GO, Seattle, Akey, Joshua M.
Publié 2012

Detecting geospatial patterns of Plasmodium falciparum parasite migration in Cambodia using optimized estimated effective migration surfaces

par Li, Yao, Shetty, Amol C., Lon, Chanthap, Spring, Michele, Saunders, David L., Fukuda, Mark M., Hien, Tran Tinh, Pukrittayakamee, Sasithon, Fairhurst, Rick M., Dondorp, Arjen M., Plowe, Christopher V., O’Connor, Timothy D., Takala-Harrison, Shannon, Stewart, Kathleen
Publié dans Int J Health Geogr (2020)

Evolutionary history of modern Samoans

par Harris, Daniel N., Kessler, Michael D., Shetty, Amol C., Weeks, Daniel E., Minster, Ryan L., Browning, Sharon, Cochrane, Ethan E., Deka, Ranjan, Hawley, Nicola L., Reupena, Muagututi‘a Sefuiva, Naseri, Take, McGarvey, Stephen T., O’Connor, Timothy D.
Publié dans Proc Natl Acad Sci U S A (2020)

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

par Kessler, Michael D., Yerges-Armstrong, Laura, Taub, Margaret A., Shetty, Amol C., Maloney, Kristin, Jeng, Linda Jo Bone, Ruczinski, Ingo, Levin, Albert M., Williams, L. Keoki, Beaty, Terri H., Mathias, Rasika A., Barnes, Kathleen C., O'Connor, Timothy D.
Publié dans Nat Commun (2016)

Evolutionary genomic dynamics of Peruvians before, during, and after the Inca Empire

par Harris, Daniel N., Song, Wei, Shetty, Amol C., Levano, Kelly S., Cáceres, Omar, Padilla, Carlos, Borda, Víctor, Tarazona, David, Trujillo, Omar, Sanchez, Cesar, Kessler, Michael D., Galarza, Marco, Capristano, Silvia, Montejo, Harrison, Flores-Villanueva, Pedro O., Tarazona-Santos, Eduardo, O’Connor, Timothy D., Guio, Heinner
Publié dans Proc Natl Acad Sci U S A (2018)

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi

par Chibucos, Marcus C., Soliman, Sameh, Gebremariam, Teclegiorgis, Lee, Hongkyu, Daugherty, Sean, Orvis, Joshua, Shetty, Amol C., Crabtree, Jonathan, Hazen, Tracy H., Etienne, Kizee A., Kumari, Priti, O'Connor, Timothy D., Rasko, David A., Filler, Scott G., Fraser, Claire M., Lockhart, Shawn R., Skory, Christopher D., Ibrahim, Ashraf S., Bruno, Vincent M.
Publié dans Nat Commun (2016)

Identifying tagging SNPs for African specific genetic variation from the African Diaspora Genome

par Johnston, Henry Richard, Hu, Yi-Juan, Gao, Jingjing, O’Connor, Timothy D., Abecasis, Gonçalo R., Wojcik, Genevieve L, Gignoux, Christopher R., Gourraud, Pierre-Antoine, Lizee, Antoine, Hansen, Mark, Genuario, Rob, Bullis, Dave, Lawley, Cindy, Kenny, Eimear E., Bustamante, Carlos, Beaty, Terri H., Mathias, Rasika A., Barnes, Kathleen C., Qin, Zhaohui S.
Publié dans Sci Rep (2017)