Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

To characterize the extent and impact of ancestry-related biases in precision genomic medicine, we use 642 whole-genome sequences from the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) project to evaluate typical filters and databases. We find significant correlatio...

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Vydáno v:Nat Commun
Hlavní autoři: Kessler, Michael D., Yerges-Armstrong, Laura, Taub, Margaret A., Shetty, Amol C., Maloney, Kristin, Jeng, Linda Jo Bone, Ruczinski, Ingo, Levin, Albert M., Williams, L. Keoki, Beaty, Terri H., Mathias, Rasika A., Barnes, Kathleen C., O'Connor, Timothy D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5062569/
https://ncbi.nlm.nih.gov/pubmed/27725664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12521
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