Analysis of 6,515 exomes reveals a recent origin of most human protein-coding variants

Establishing the age of each mutation segregating in contemporary human populations is important to fully understand our evolutionary history(1,2) and will help facilitate the development of new approaches for disease gene discovery(3). Large-scale surveys of human genetic variation have reported si...

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Detalhes bibliográficos
Main Authors: Fu, Wenqing, O'Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., GO, Broad, GO, Seattle, Akey, Joshua M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3676746/
https://ncbi.nlm.nih.gov/pubmed/23201682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11690
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