Turning Receptors On and Off with Intracellular Pepducins: New Insights into G-protein-coupled Receptor Drug Development

Por O'Callaghan, Katie, Kuliopulos, Athan, Covic, Lidija
Publicado em 2012

Matrix Metalloprotease-1a Promotes Tumorigenesis and Metastasis

Por Foley, Caitlin J., Luo, Chi, O'Callaghan, Katie, Hinds, Philip W., Covic, Lidija, Kuliopulos, Athan
Publicado em 2012

Blockade of PAR1 signaling with cell-penetrating pepducins inhibits Akt-survival pathways in breast cancer cells and suppresses tumor survival and metastasis

Por Yang, Eric, Boire, Adrienne, Agarwal, Anika, Nguyen, Nga, O'Callaghan, Katie, Tu, Powen, Kuliopulos, Athan, Covic, Lidija
Publicado em 2009

Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis By Activating PAR1 at a Cryptic Ligand Site

Por Trivedi, Vishal, Boire, Adrienne, Tchernychev, Boris, Kaneider, Nicole C., Leger, Andrew J., O’Callaghan, Katie, Covic, Lidija, Kuliopulos, Athan
Publicado em 2009

Heme-binding Protein HRG-1 Is Induced by Insulin-like Growth Factor I and Associates with the Vacuolar H(+)-ATPase to Control Endosomal pH and Receptor Trafficking

Por O'Callaghan, Katie M., Ayllon, Veronica, O'Keeffe, Jean, Wang, Yanru, Cox, Orla T., Loughran, Gary, Forgac, Michael, O'Connor, Rosemary
Publicado em 2010

Suppression of Arterial Thrombosis without Affecting Hemostatic Parameters with A Cell-Penetrating PAR1 Pepducin

Por Zhang, Ping, Gruber, András, Kasuda, Shogo, Kimmelstiel, Carey, O’Callaghan, Katie, Cox, Daniel H., Bohm, Andrew, Baleja, James D., Covic, Lidija, Kuliopulos, Athan
Publicado em 2012

Targeting CXCR4 with cell-penetrating pepducins in lymphoma and lymphocytic leukemia

Por O'Callaghan, Katie, Lee, Lydia, Nguyen, Nga, Hsieh, Mo-Ying, Kaneider, Nicole C., Klein, Andreas K., Sprague, Kellie, Van Etten, Richard A., Kuliopulos, Athan, Covic, Lidija
Publicado em 2012

Targeting Protease-Activated Receptor-1 with Cell-Penetrating Pepducins in Lung Cancer

Por Cisowski, Jaroslaw, O'Callaghan, Katie, Kuliopulos, Athan, Yang, John, Nguyen, Nga, Deng, Qing, Yang, Eric, Fogel, Michael, Tressel, Sarah, Foley, Caitlin, Agarwal, Anika, Hunt, Stephen W., McMurry, Tom, Brinckerhoff, Larry, Covic, Lidija
Publicado em 2011

The Insulin-like Growth Factor-I–mTOR Signaling Pathway Induces the Mitochondrial Pyrimidine Nucleotide Carrier to Promote Cell Growth

Por Floyd, Suzanne, Favre, Cedric, Lasorsa, Francesco M., Leahy, Madeline, Trigiante, Giuseppe, Stroebel, Philipp, Marx, Alexander, Loughran, Gary, O'Callaghan, Katie, Marobbio, Carlo M.T., Slotboom, Dirk J., Kunji, Edmund R.S., Palmieri, Ferdinando, O'Connor, Rosemary
Publicado em 2007

HSP90 Inhibition Enhances Antimitotic Drug-Induced Mitotic Arrest and Cell Death in Preclinical Models of Non-Small Cell Lung Cancer

Por O'Connell, Brenda C., O'Callaghan, Katie, Tillotson, Bonnie, Douglas, Mark, Hafeez, Nafeeza, West, Kip A., Stern, Howard, Ali, Janid A., Changelian, Paul, Fritz, Christian C., Palombella, Vito J., McGovern, Karen, Kutok, Jeffery L.
Publicado no PLoS One (2014)