Cartilage preservation by inhibition of Janus kinase 3 in two rodent models of rheumatoid arthritis

Por Milici, Anthony J, Kudlacz, Elizabeth M, Audoly, Laurent, Zwillich, Samuel, Changelian, Paul
Publicado em 2008

Jakinibs: A New Class of Kinase Inhibitors in Cancer and Autoimmune Disease

Por Kontzias, Apostolos, Kotlyar, Alexander, Laurence, Arian, Changelian, Paul, O’Shea, John J.
Publicado em 2012

Ecto-5′-Nucleotidase (CD73) Attenuates Allograft Airway Rejection through Adenosine 2A Receptor Stimulation

Por Ohtsuka, Takashi, Changelian, Paul S., Bouïs, Diane, Noon, Kathleen, Harada, Hiroaki, Lama, Vibha N., Pinsky, David J.
Publicado em 2010

The amino terminus of JAK3 is necessary and sufficient for binding to the common γ chain and confers the ability to transmit interleukin 2-mediated signals

Por Chen, Min, Cheng, Alan, Chen, Yi-Qing, Hymel, Anka, Hanson, Eric P., Kimmel, Lida, Minami, Yasuhiro, Taniguchi, Tadatsugu, Changelian, Paul S., O’Shea, John J.
Publicado em 1997

Proline Residues in Cd28 and the Src Homology (Sh)3 Domain of Lck Are Required for T Cell Costimulation

Por Holdorf, Amy D., Green, Jonathan M., Levin, Steven D., Denny, Michael F., Straus, David B., Link, Vinzenz, Changelian, Paul S., Allen, Paul M., Shaw, Andrey S.
Publicado em 1999

Distinct tyrosine phosphorylation sites in JAK3 kinase domain positively and negatively regulate its enzymatic activity

Por Zhou, Yong-Jie, Hanson, Eric P., Chen, Yi-Qing, Magnuson, Kelly, Chen, Min, Swann, Patrick G., Wange, Ronald L., Changelian, Paul S., O’Shea, John J.
Publicado em 1997

Hierarchy of Protein Tyrosine Kinases in Interleukin-2 (IL-2) Signaling: Activation of Syk Depends on Jak3; However, Neither Syk nor Lck Is Required for IL-2-Mediated STAT Activat...

Por Zhou, Yong-Jie, Magnuson, Kelly S., Cheng, Tammy P., Gadina, Massimo, Frucht, David M., Galon, Jerome, Candotti, Fabio, Geahlen, Robert L., Changelian, Paul S., O'Shea, John J.
Publicado em 2000

HSP90 Inhibition Enhances Antimitotic Drug-Induced Mitotic Arrest and Cell Death in Preclinical Models of Non-Small Cell Lung Cancer

Por O'Connell, Brenda C., O'Callaghan, Katie, Tillotson, Bonnie, Douglas, Mark, Hafeez, Nafeeza, West, Kip A., Stern, Howard, Ali, Janid A., Changelian, Paul, Fritz, Christian C., Palombella, Vito J., McGovern, Karen, Kutok, Jeffery L.
Publicado no PLoS One (2014)