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Jakinibs: A New Class of Kinase Inhibitors in Cancer and Autoimmune Disease
Cytokines are critical for normal cell growth and immunoregulation but also contribute to growth of malignant cells and drive immune-mediated disease. A major subset of immunoregulatory cytokines, roughly 60, use the type I and type II cytokine receptors and pharmacological targeting of these cytoki...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3419278/ https://ncbi.nlm.nih.gov/pubmed/22819198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2012.06.008 |
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