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Jakinibs: A New Class of Kinase Inhibitors in Cancer and Autoimmune Disease

Cytokines are critical for normal cell growth and immunoregulation but also contribute to growth of malignant cells and drive immune-mediated disease. A major subset of immunoregulatory cytokines, roughly 60, use the type I and type II cytokine receptors and pharmacological targeting of these cytoki...

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Detalles Bibliográficos
Main Authors: Kontzias, Apostolos, Kotlyar, Alexander, Laurence, Arian, Changelian, Paul, O’Shea, John J.
Formato: Artigo
Idioma:Inglês
Publicado: 2012
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3419278/
https://ncbi.nlm.nih.gov/pubmed/22819198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coph.2012.06.008
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