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Kinase inhibitors in the treatment of immune-mediated disease
Protein kinases are fundamental components of diverse signaling pathways, including immune cells. Their essential functions have made them effective therapeutic targets. Initially, the expectation was that a high degree of selectivity would be critical; however, with time, the use of “multikinase” i...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Faculty of 1000 Ltd
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3297200/ https://ncbi.nlm.nih.gov/pubmed/22403586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3410/M4-5 |
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