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Janus kinases to jakinibs: from basic insights to clinical practice

Cytokines are critical mediators of diverse immune and inflammatory diseases. Targeting cytokines and cytokine receptors with biologics has revolutionized the treatment of many of these diseases, but targeting intracellular signalling with Janus kinase (JAK) inhibitors (jakinibs) now represents a ma...

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Podrobná bibliografie
Vydáno v:Rheumatology (Oxford)
Hlavní autoři: Gadina, Massimo, Le, Mimi T, Schwartz, Daniella M, Silvennoinen, Olli, Nakayamada, Shingo, Yamaoka, Kunihiro, O’Shea, John J
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657570/
https://ncbi.nlm.nih.gov/pubmed/30806710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/key432
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