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Janus kinases to jakinibs: from basic insights to clinical practice

Cytokines are critical mediators of diverse immune and inflammatory diseases. Targeting cytokines and cytokine receptors with biologics has revolutionized the treatment of many of these diseases, but targeting intracellular signalling with Janus kinase (JAK) inhibitors (jakinibs) now represents a ma...

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Detalles Bibliográficos
Publicado en:Rheumatology (Oxford)
Main Authors: Gadina, Massimo, Le, Mimi T, Schwartz, Daniella M, Silvennoinen, Olli, Nakayamada, Shingo, Yamaoka, Kunihiro, O’Shea, John J
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657570/
https://ncbi.nlm.nih.gov/pubmed/30806710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/key432
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