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Janus kinases to jakinibs: from basic insights to clinical practice

Cytokines are critical mediators of diverse immune and inflammatory diseases. Targeting cytokines and cytokine receptors with biologics has revolutionized the treatment of many of these diseases, but targeting intracellular signalling with Janus kinase (JAK) inhibitors (jakinibs) now represents a ma...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Rheumatology (Oxford)
Hauptverfasser: Gadina, Massimo, Le, Mimi T, Schwartz, Daniella M, Silvennoinen, Olli, Nakayamada, Shingo, Yamaoka, Kunihiro, O’Shea, John J
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6657570/
https://ncbi.nlm.nih.gov/pubmed/30806710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/rheumatology/key432
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