Platelet Matrix Metalloprotease-1 Mediates Thrombogenesis By Activating PAR1 at a Cryptic Ligand Site

Matrix metalloproteases (MMPs) play many important roles in normal and pathological remodeling processes including atherothrombotic disease, inflammation, angiogenesis and cancer. Traditionally, MMPs have been viewed as matrix-degrading enzymes, but recent studies have shown that they possess direct...

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Detalhes bibliográficos
Main Authors: Trivedi, Vishal, Boire, Adrienne, Tchernychev, Boris, Kaneider, Nicole C., Leger, Andrew J., O’Callaghan, Katie, Covic, Lidija, Kuliopulos, Athan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2807741/
https://ncbi.nlm.nih.gov/pubmed/19379698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.02.018
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