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Matrix Metalloprotease-1a Promotes Tumorigenesis and Metastasis

Matrix metalloprotease-1 (MMP1), a collagenase and activator of the G protein-coupled protease activated receptor-1 (PAR1), is an emerging new target implicated in oncogenesis and metastasis in diverse cancers. However, the functional mouse homologue of MMP1 in cancer models has not yet been clearly...

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Main Authors: Foley, Caitlin J., Luo, Chi, O'Callaghan, Katie, Hinds, Philip W., Covic, Lidija, Kuliopulos, Athan
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3397859/
https://ncbi.nlm.nih.gov/pubmed/22573325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.356303
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