Targeting Protease-Activated Receptor-1 with Cell-Penetrating Pepducins in Lung Cancer

Protease-activated receptors (PARs) are G-protein–coupled receptors that are activated by proteolytic cleavage and generation of a tethered ligand. High PAR1 expression has been documented in a variety of invasive cancers of epithelial origin. In the present study, we investigated the contribution o...

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Detalhes bibliográficos
Main Authors: Cisowski, Jaroslaw, O'Callaghan, Katie, Kuliopulos, Athan, Yang, John, Nguyen, Nga, Deng, Qing, Yang, Eric, Fogel, Michael, Tressel, Sarah, Foley, Caitlin, Agarwal, Anika, Hunt, Stephen W., McMurry, Tom, Brinckerhoff, Larry, Covic, Lidija
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2011
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3123854/
https://ncbi.nlm.nih.gov/pubmed/21703428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.03.025
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