INTERSECTINg Pathways in Cell Biology

Por O'Bryan, John P.
Publicado em 2010

Intersectin 1 is required for neuroblastoma tumorigenesis

Por Russo, Angela, O'Bryan, John P.
Publicado em 2012

Bimolecular Fluorescence Complementation

Por Wong, Katy A., O'Bryan, John P.
Publicado em 2011

Intersectin scaffold proteins and their role in cell signaling and endocytosis

Por Herrero-Garcia, Erika, O’Bryan., John P.
Publicado no Biochim Biophys Acta (2016)

Emerging Roles for Intersectin (ITSN) in Regulating Signaling and Disease Pathways

Por Hunter, Michael P., Russo, Angela, O’Bryan, John P.
Publicado em 2013

Receptor Tyrosine Kinase Ubiquitylation Involves the Dynamic Regulation of Cbl-Spry2 by Intersectin 1 and the Shp2 Tyrosine Phosphatase

Por Okur, Mustafa Nazir, Russo, Angela, O'Bryan, John P.
Publicado em 2014

Phosphatidylinositol 3-kinase, Class 2 beta (PI3KC2β) isoform contributes to neuroblastoma tumorigenesis

Por Russo, Angela, Okur, Mustafa Nazir, Bosland, Maarten, O'Bryan, John P.
Publicado no Cancer Lett (2015)

Cooperative Role of Caveolin-1 and C-Terminal Src Kinase Binding Protein in C-Terminal Src Kinase-Mediated Negative Regulation of c-Src

Por Place, Aaron T., Chen, Zhenlong, Bakhshi, Farnaz R., Liu, Guoquan, O'Bryan, John P., Minshall, Richard D.
Publicado em 2011

Cardiac-Specific Expression of the Tetracycline Transactivator Confers Increased Heart Function and Survival Following Ischemia Reperfusion Injury

Por Elsherif, Laila, Wang, Xuerong, Grachoff, Milana, Wolska, Beata M., Geenen, David L., O'Bryan, John P.
Publicado em 2012

A New Dimension to Ras Function: A Novel Role for Nucleotide-Free Ras in Class II Phosphatidylinositol 3-Kinase Beta (PI3KC2β) Regulation

Por Wong, Katy A., Russo, Angela, Wang, Xuerong, Chen, Yun-Ju, Lavie, Arnon, O'Bryan, John P.
Publicado em 2012

Silencing Intersectin 1 Slows Orthotopic Neuroblastoma Growth in Mice

Por Harris, Jamie, Herrero-Garcia, Erika, Russo, Angela, Kajdacsy-Balla, Andre, O’Bryan, John P., Chiu, Bill
Publicado no J Pediatr Hematol Oncol (2017)

Protein Kinase A (PKA) Phosphorylation of Shp2 Protein Inhibits Its Phosphatase Activity and Modulates Ligand Specificity

Por Burmeister, Brian T., Wang, Li, Gold, Matthew G., Skidgel, Randal A., O'Bryan, John P., Carnegie, Graeme K.
Publicado no J Biol Chem (2015)

The Ubiquitin-interacting Motif Protein, S5a, Is Ubiquitinated by All Types of Ubiquitin Ligases by a Mechanism Different from Typical Substrate Recognition

Por Uchiki, Tomoaki, Kim, Hyoung Tae, Zhai, Bo, Gygi, Steven P., Johnston, Jennifer A., O'Bryan, John P., Goldberg, Alfred L.
Publicado em 2009

N-type Ca(2+) channels as scaffold proteins in the assembly of signaling molecules for GABA(B) receptor effects.

Por Richman, Ryan W., Tombler, Eugene, Lau, King Kei, Anantharam, Arun, Rodriguez, Jennifer, O'Bryan, John P., Diversé-Pierluissi, María A.
Publicado em 2011

Intersectin 1 contributes to phenotypes in vivo: implications for Down Syndrome

Por Hunter, Michael P., Nelson, Marianela, Kurzer, Michael, Wang, Xuerong, Kryscio, Richard J., Head, Elizabeth, Pinna, Graziano, O’Bryan, John P.
Publicado em 2011

Intersectin 1 Enhances Cbl Ubiquitylation of Epidermal Growth Factor Receptor through Regulation of Sprouty2-Cbl Interaction

Por Okur, Mustafa Nazir, Ooi, Jolene, Fong, Chee Wai, Martinez, Natalia, Garcia-Dominguez, Carlota, Rojas, Jose M., Guy, Graeme, O'Bryan, John P.
Publicado em 2012

UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy

Por Wang, Li, Burmeister, Brian T., Johnson, Keven R., Baillie, George S., Karginov, Andrei V., Skidgel, Randal A., O’Bryan, John P., Carnegie, Graeme K.
Publicado no Cell Signal (2015)

Regulation of Neuron Survival through an Intersectin-Phosphoinositide 3′-Kinase C2β-AKT Pathway

Por Das, Margaret, Scappini, Erica, Martin, Negin P., Wong, Katy A., Dunn, Sara, Chen, Yun-Ju, Miller, Stephanie L. H., Domin, Jan, O'Bryan, John P.
Publicado em 2007

Intersectin (ITSN) Family of Scaffolds Function as Molecular Hubs in Protein Interaction Networks

Por Wong, Katy A., Wilson, Jessica, Russo, Angela, Wang, Li, Okur, Mustafa Nazir, Wang, Xuerong, Martin, Negin P., Scappini, Erica, Carnegie, Graeme K., O'Bryan, John P.
Publicado em 2012

Akt2 Stabilizes ATP7A, a Cu transporter for SOD3, in Vascular Smooth Muscles: Novel Mechanism to limit Endothelial Dysfunction in Type2 diabetes

Por Sudhahar, Varadarajan, Okur, Mustafa Nazir, Bagi, Zsolt, O'Bryan, John P, Hay, Nissim, Makino, Ayako, Patel, Vijay S, Phillips, Shane A, Stepp, David, Ushio-Fukai, Masuko, Fukai, Tohru
Publicado no Arterioscler Thromb Vasc Biol (2018)