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UCR1C is a novel activator of phosphodiesterase 4 (PDE4) long isoforms and attenuates cardiomyocyte hypertrophy

Hypertrophy increases the risk of heart failure and arrhythmia. Prevention or reversal of the maladaptive hypertrophic phenotype has thus been proposed to treat heart failure. Chronic β-adrenergic receptor (β-AR) stimulation induces cardiomyocyte hypertrophy by elevating 3′, 5′-cyclic adenosine mono...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Cell Signal
Asıl Yazarlar: Wang, Li, Burmeister, Brian T., Johnson, Keven R., Baillie, George S., Karginov, Andrei V., Skidgel, Randal A., O’Bryan, John P., Carnegie, Graeme K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4361369/
https://ncbi.nlm.nih.gov/pubmed/25683917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2015.02.003
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