Proton Conductivity through the Human TRPM7 Channel and Its Molecular Determinants

Por Numata, Tomohiro, Okada, Yasunobu
Publicado em 2008

A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl(-) channel

Por Shimizu, Takahiro, Numata, Tomohiro, Okada, Yasunobu
Publicado em 2004

Pathophysiology and puzzles of the volume-sensitive outwardly rectifying anion channel

Por Okada, Yasunobu, Sato, Kaori, Numata, Tomohiro
Publicado em 2009

“TRP inflammation” relationship in cardiovascular system

Por Numata, Tomohiro, Takahashi, Kiriko, Inoue, Ryuji
Publicado no Semin Immunopathol (2015)

Temperature sensitivity of acid-sensitive outwardly rectifying (ASOR) anion channels in cortical neurons is involved in hypothermic neuroprotection against acidotoxic necrosis

Por Sato-Numata, Kaori, Numata, Tomohiro, Okada, Yasunobu
Publicado em 2014

Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis

Por Numata, Tomohiro, Sato, Kaori, Okada, Yasunobu, Wehner, Frank
Publicado em 2008

Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line

Por Badr, Heba, Kozai, Daisuke, Sakaguchi, Reiko, Numata, Tomohiro, Mori, Yasuo
Publicado no Front Pharmacol (2016)

Distinct contributions of LRRC8A and its paralogs to the VSOR anion channel from those of the ASOR anion channel

Por Sato-Numata, Kaori, Numata, Tomohiro, Inoue, Ryuji, Sabirov, Ravshan Z., Okada, Yasunobu
Publicado no Channels (Austin) (2016)

The ΔC splice-variant of TRPM2 is the hypertonicity-induced cation channel in HeLa cells, and the ecto-enzyme CD38 mediates its activation

Por Numata, Tomohiro, Sato, Kaori, Christmann, Jens, Marx, Romy, Mori, Yasuo, Okada, Yasunobu, Wehner, Frank
Publicado em 2012

Novel HCN2 Mutation Contributes to Febrile Seizures by Shifting the Channel's Kinetics in a Temperature-Dependent Manner

Por Nakamura, Yuki, Shi, Xiuyu, Numata, Tomohiro, Mori, Yasuo, Inoue, Ryuji, Lossin, Christoph, Baram, Tallie Z., Hirose, Shinichi
Publicado em 2013

Active Zone Protein Bassoon Co-Localizes with Presynaptic Calcium Channel, Modifies Channel Function, and Recovers from Aging Related Loss by Exercise

Por Nishimune, Hiroshi, Numata, Tomohiro, Chen, Jie, Aoki, Yudai, Wang, Yonghong, Starr, Miranda P., Mori, Yasuo, Stanford, John A.
Publicado em 2012

The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations

Por Chen Xuanmao, Numata Tomohiro, Li Minghua, Mori Yasuo, Orser Beverley A, Jackson Michael F, Xiong Zhi-Gang, MacDonald John F
Publicado em 2010-12-01

The modulation of TRPM7 currents by nafamostat mesilate depends directly upon extracellular concentrations of divalent cations

Por Chen, Xuanmao, Numata, Tomohiro, Li, Minghua, Mori, Yasuo, Orser, Beverley A, Jackson, Michael F, Xiong, Zhi-Gang, MacDonald, John F
Publicado em 2010

Cold sensitivity of TRPA1 is unveiled by the prolyl hydroxylation blockade-induced sensitization to ROS

Por Miyake, Takahito, Nakamura, Saki, Zhao, Meng, So, Kanako, Inoue, Keisuke, Numata, Tomohiro, Takahashi, Nobuaki, Shirakawa, Hisashi, Mori, Yasuo, Nakagawa, Takayuki, Kaneko, Shuji
Publicado no Nat Commun (2016)

TRPM1 is a component of the retinal ON bipolar cell transduction channel in the mGluR6 cascade

Por Koike, Chieko, Obara, Takehisa, Uriu, Yoshitsugu, Numata, Tomohiro, Sanuki, Rikako, Miyata, Kentarou, Koyasu, Toshiyuki, Ueno, Shinji, Funabiki, Kazuo, Tani, Akiko, Ueda, Hiroshi, Kondo, Mineo, Mori, Yasuo, Tachibana, Masao, Furukawa, Takahisa
Publicado em 2009

Ablation of the N-type calcium channel ameliorates diabetic nephropathy with improved glycemic control and reduced blood pressure

Por Ohno, Shoko, Yokoi, Hideki, Mori, Kiyoshi, Kasahara, Masato, Kuwahara, Koichiro, Fujikura, Junji, Naito, Masaki, Kuwabara, Takashige, Imamaki, Hirotaka, Ishii, Akira, Saleem, Moin A., Numata, Tomohiro, Mori, Yasuo, Nakao, Kazuwa, Yanagita, Motoko, Mukoyama, Masashi
Publicado no Sci Rep (2016)

A Pathogenic C Terminus-truncated Polycystin-2 Mutant Enhances Receptor-activated Ca(2+) Entry via Association with TRPC3 and TRPC7

Por Miyagi, Kyoko, Kiyonaka, Shigeki, Yamada, Kazunori, Miki, Takafumi, Mori, Emiko, Kato, Kenta, Numata, Tomohiro, Sawaguchi, Yuichi, Numaga, Takuro, Kimura, Toru, Kanai, Yoshikatsu, Kawano, Mitsuhiro, Wakamori, Minoru, Nomura, Hideki, Koni, Ichiro, Yamagishi, Masakazu, Mori, Yasuo
Publicado em 2009

Selective and direct inhibition of TRPC3 channels underlies biological activities of a pyrazole compound

Por Kiyonaka, Shigeki, Kato, Kenta, Nishida, Motohiro, Mio, Kazuhiro, Numaga, Takuro, Sawaguchi, Yuichi, Yoshida, Takashi, Wakamori, Minoru, Mori, Emiko, Numata, Tomohiro, Ishii, Masakazu, Takemoto, Hiroki, Ojida, Akio, Watanabe, Kenta, Uemura, Aya, Kurose, Hitoshi, Morii, Takashi, Kobayashi, Tsutomu, Sato, Yoji, Sato, Chikara, Hamachi, Itaru, Mori, Yasuo
Publicado em 2009

Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models

Por Ameku, Tomonaga, Taura, Daisuke, Sone, Masakatsu, Numata, Tomohiro, Nakamura, Masahiro, Shiota, Fumihiko, Toyoda, Taro, Matsui, Satoshi, Araoka, Toshikazu, Yasuno, Tetsuhiko, Mae, Shin-Ichi, Kobayashi, Hatasu, Kondo, Naoya, Kitaoka, Fumiyo, Amano, Naoki, Arai, Sayaka, Ichisaka, Tomoko, Matsuura, Norio, Inoue, Sumiko, Yamamoto, Takuya, Takahashi, Kazutoshi, Asaka, Isao, Yamada, Yasuhiro, Ubara, Yoshifumi, Muso, Eri, Fukatsu, Atsushi, Watanabe, Akira, Sato, Yasunori, Nakahata, Tatsutoshi, Mori, Yasuo, Koizumi, Akio, Nakao, Kazuwa, Yamanaka, Shinya, Osafune, Kenji
Publicado no Sci Rep (2016)