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A role of reactive oxygen species in apoptotic activation of volume-sensitive Cl(-) channel

Apoptotic volume decrease is a pivotal event triggering a cell to undergo apoptosis and is induced by ionic effluxes resulting mainly from increased K(+) and Cl(-) conductances. Here, we demonstrate that in human epithelia HeLa cells both mitochondrion- and death receptor-mediated apoptosis inducers...

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Detalhes bibliográficos
Main Authors: Shimizu, Takahiro, Numata, Tomohiro, Okada, Yasunobu
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC404120/
https://ncbi.nlm.nih.gov/pubmed/15096609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401604101
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