Novel HCN2 Mutation Contributes to Febrile Seizures by Shifting the Channel's Kinetics in a Temperature-Dependent Manner

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channel-mediated currents, known as I (h), are involved in the control of rhythmic activity in neuronal circuits and in determining neuronal properties including the resting membrane potential. Recent studies have shown that HCN channels play...

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Detalhes bibliográficos
Main Authors: Nakamura, Yuki, Shi, Xiuyu, Numata, Tomohiro, Mori, Yasuo, Inoue, Ryuji, Lossin, Christoph, Baram, Tallie Z., Hirose, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3851455/
https://ncbi.nlm.nih.gov/pubmed/24324597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0080376
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