Mechanism-Based Inactivation of Human Cytochrome P450 3A4 by Two Piperazine-Containing Compounds

由 Bolles, Amanda K., Fujiwara, Rina, Briggs, Erran D., Nomeir, Amin A., Furge, Laura Lowe
發表在 Drug Metab Dispos (2014)

Pharmacokinetics of SCH 56592, a New Azole Broad-Spectrum Antifungal Agent, in Mice, Rats, Rabbits, Dogs, and Cynomolgus Monkeys

由 Nomeir, Amin A., Kumari, Pramila, Hilbert, Mary Jane, Gupta, Samir, Loebenberg, David, Cacciapuoti, Anthony, Hare, Roberta, Miller, George H., Lin, Chin-Chung, Cayen, Mitchell N.
出版 2000

Substituted Imidazole of 5-Fluoro-2-[4-[(2-phenyl-1H-imidazol-5-yl)methyl]-1-piperazinyl]pyrimidine Inactivates Cytochrome P450 2D6 by Protein Adduction

由 Nagy, Leslie D., Mocny, Catherine S., Diffenderfer, Laura E., Hsi, David J., Butler, Brendan F., Arthur, Evan J., Fletke, Kyle J., Palamanda, Jairam R., Nomeir, Amin A., Furge, Laura Lowe
出版 2011

In Vivo Characterization of a Novel γ-Secretase Inhibitor SCH 697466 in Rodents and Investigation of Strategies for Managing Notch-Related Side Effects

由 Hyde, Lynn A., Zhang, Qi, Del Vecchio, Robert A., Leach, Prescott T., Cohen-Williams, Mary E., Chen, Lei, Wong, Gwendolyn T., McHugh, Nansie A., Chen, Joseph, Higgins, Guy A., Asberom, Theodros, Li, Wei, Pissarnitski, Dmitri, Levitan, Diane, Nomeir, Amin A., Clader, John W., Zhang, Lili, Parker, Eric M.
出版 2013

Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein

由 Gu, Zhengxian, Graci, Jason D., Lahser, Frederick C., Breslin, Jamie J., Jung, Stephen P., Crona, James H., McMonagle, Patricia, Xia, Ellen, Liu, Shaotang, Karp, Gary, Zhu, Jin, Huang, Song, Nomeir, Amin, Weetall, Marla, Almstead, Neil G., Peltz, Stuart W., Tong, Xiao, Ralston, Robert, Colacino, Joseph M.
出版 2013

Discovery of SCH 900229, a Potent Presenilin 1 Selective γ-Secretase Inhibitor for the Treatment of Alzheimer’s Disease

由 Wu, Wen-Lian, Domalski, Martin, Burnett, Duane A., Josien, Hubert, Bara, Thomas, Rajagopalan, Murali, Xu, Ruo, Clader, John, Greenlee, William J., Brunskill, Andrew, Hyde, Lynn A., Del Vecchio, Robert A., Cohen-Williams, Mary E., Song, Lixin, Lee, Julie, Terracina, Giuseppe, Zhang, Qi, Nomeir, Amin, Parker, Eric M., Zhang, Lili
出版 2012

Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors

由 Bogen, Stéphane L., Pan, Weidong, Gibeau, Craig R., Lahue, Brian R., Ma, Yao, Nair, Latha G., Seigel, Elise, Shipps, Gerald W., Tian, Yuan, Wang, Yaolin, Lin, Yinghui, Liu, Ming, Liu, Suxing, Mirza, Asra, Wang, Xiaoying, Lipari, Philip, Seidel-Dugan, Cynthia, Hicklin, Daniel J., Bishop, W. Robert, Rindgen, Diane, Nomeir, Amin, Prosise, Winifred, Reichert, Paul, Scapin, Giovanna, Strickland, Corey, Doll, Ronald J.
發表在 ACS Med Chem Lett (2016)

Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases

由 Paruch, Kamil, Dwyer, Michael P., Alvarez, Carmen, Brown, Courtney, Chan, Tin-Yau, Doll, Ronald J., Keertikar, Kerry, Knutson, Chad, McKittrick, Brian, Rivera, Jocelyn, Rossman, Randall, Tucker, Greg, Fischmann, Thierry, Hruza, Alan, Madison, Vincent, Nomeir, Amin A., Wang, Yaolin, Kirschmeier, Paul, Lees, Emma, Parry, David, Sgambellone, Nicole, Seghezzi, Wolfgang, Schultz, Lesley, Shanahan, Frances, Wiswell, Derek, Xu, Xiaoying, Zhou, Quiao, James, Ray A., Paradkar, Vidyadhar M., Park, Haengsoon, Rokosz, Laura R., Stauffer, Tara M., Guzi, Timothy J.
出版 2010