Identification of PTC725, an Orally Bioavailable Small Molecule That Selectively Targets the Hepatitis C Virus NS4B Protein

While new direct-acting antiviral agents for the treatment of chronic hepatitis C virus (HCV) infection have been approved, there is a continued need for novel antiviral agents that act on new targets and can be used in combination with current therapies to enhance efficacy and to restrict the emerg...

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Detalhes bibliográficos
Main Authors: Gu, Zhengxian, Graci, Jason D., Lahser, Frederick C., Breslin, Jamie J., Jung, Stephen P., Crona, James H., McMonagle, Patricia, Xia, Ellen, Liu, Shaotang, Karp, Gary, Zhu, Jin, Huang, Song, Nomeir, Amin, Weetall, Marla, Almstead, Neil G., Peltz, Stuart W., Tong, Xiao, Ralston, Robert, Colacino, Joseph M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3697315/
https://ncbi.nlm.nih.gov/pubmed/23629699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00527-13
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