HIV Latency Gets a New Histone Mark

Por Nikolai, Bryan C., Feng, Qin
Publicado no Cell Host Microbe (2017)

Proteomic Profiling of a Primary CD4(+) T Cell Model of HIV-1 Latency Identifies Proteins Whose Differential Expression Correlates with Reactivation of Latent HIV-1

Por Saha, Jamaluddin Md, Liu, Hongbing, Hu, Pei-Wen, Nikolai, Bryan C., Wu, Hulin, Miao, Hongyu, Rice, Andrew P.
Publicado no AIDS Res Hum Retroviruses (2018)

USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

Por Padmanabhan, Achuth, Candelaria, Nicholes, Wong, Kwong-Kwok, Nikolai, Bryan C., Lonard, David M., O’Malley, Bert W., Richards, JoAnne S.
Publicado no Nat Commun (2018)

Reprogramming the posttranslational code of SRC-3 confers a switch in mammalian systems biology

Por York, Brian, Yu, Chundong, Sagen, Jørn V., Liu, Zhaoliang, Nikolai, Bryan C., Wu, Ray-Chang, Finegold, Milton, Xu, Jianming, O'Malley, Bert W.
Publicado em 2010

Crosstalk between histone modifications indicates that inhibition of arginine methyltransferase CARM1 activity reverses HIV latency

Por Zhang, Zheng, Nikolai, Bryan C., Gates, Leah A., Jung, Sung Yun, Siwak, Edward B., He, Bin, Rice, Andrew P., O’Malley, Bert W., Feng, Qin
Publicado no Nucleic Acids Res (2017)

Steroid receptor coactivator 3 (SRC-3/AIB1) is enriched and functional in mouse and human Tregs

Por Nikolai, Bryan C., Jain, Prashi, Cardenas, David L., York, Brian, Feng, Qin, McKenna, Neil J., Dasgupta, Subhamoy, Lonard, David M., O’Malley, Bert W.
Publicado no Sci Rep (2021)

HER2 signaling drives DNA anabolism and proliferation through SRC-3 phosphorylation and E2F1-regulated genes

Por Nikolai, Bryan C., Lanz, Rainer B., York, Brian, Dasgupta, Subhamoy, Mitsiades, Nicholas, Creighton, Chad J., Tsimelzon, Anna, Hilsenbeck, Susan G., Lonard, David M., Smith, Carolyn L., O’Malley, Bert W.
Publicado no Cancer Res (2016)

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer

Por Dasgupta, Subhamoy, Rajapakshe, Kimal, Zhu, Bokai, Nikolai, Bryan C., Yi, Ping, Putluri, Nagireddy, Choi, Jong Min, Jung, Sung Y., Coarfa, Cristian, Westbrook, Thomas F., Zhang, Xiang H.-F., Foulds, Charles E., Tsai, Sophia Y., Tsai, Ming-Jer, O’Malley, Bert W.
Publicado no Nature (2018)

Ablation of Steroid Receptor Coactivator-3 resembles the human CACT metabolic myopathy

Por York, Brian, Reineke, Erin L., Sagen, Jørn V., Nikolai, Bryan C., Zhou, Suoling, Louet, Jean-Francois, Chopra, Atul R., Chen, Xian, Reed, Graham, Noebels, Jeffrey, Adesina, Adekunle M., Yu, Hui, Wong, Lee-Jun C., Tsimelzon, Anna, Hilsenbeck, Susan, Stevens, Robert D., Wenner, Brett R., Ilkayeva, Olga, Xu, Jianming, Newgard, Christopher B., O’Malley, Bert W.
Publicado em 2012