Ablation of Steroid Receptor Coactivator-3 resembles the human CACT metabolic myopathy

Oxidation of lipid substrates is essential for survival in fasting and other catabolic conditions, sparing glucose for the brain and other glucose-dependent tissues. Here we show Steroid Receptor Coactivator-3 (SRC-3) plays a central role in long chain fatty acid metabolism by directly regulating ca...

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Detalhes bibliográficos
Main Authors: York, Brian, Reineke, Erin L., Sagen, Jørn V., Nikolai, Bryan C., Zhou, Suoling, Louet, Jean-Francois, Chopra, Atul R., Chen, Xian, Reed, Graham, Noebels, Jeffrey, Adesina, Adekunle M., Yu, Hui, Wong, Lee-Jun C., Tsimelzon, Anna, Hilsenbeck, Susan, Stevens, Robert D., Wenner, Brett R., Ilkayeva, Olga, Xu, Jianming, Newgard, Christopher B., O’Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3349072/
https://ncbi.nlm.nih.gov/pubmed/22560224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2012.03.020
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