Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease

Hepatic glucose production is critical for basal brain function and survival when dietary glucose is unavailable. Glucose-6-phosphatase (G6Pase) is an essential, rate-limiting enzyme that serves as a terminal gatekeeper for hepatic glucose release into the plasma. Mutations in G6Pase result in Von G...

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Main Authors: Chopra, Atul R., Louet, Jean-Francois, Saha, Pradip, An, Jie, DeMayo, Franco, Xu, Jianming, York, Brian, Karpen, Saul, Finegold, Milton, Moore, David, Chan, Lawrence, Newgard, Christopher B., O'Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668604/
https://ncbi.nlm.nih.gov/pubmed/19039140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1164847
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