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Proteomic Profiling of a Primary CD4(+) T Cell Model of HIV-1 Latency Identifies Proteins Whose Differential Expression Correlates with Reactivation of Latent HIV-1

The latent HIV-1 reservoir of memory CD4(+) T cells that persists during combination antiviral therapy prevents a cure of infection. Insight into mechanisms of latency and viral reactivation are essential for the rational design of strategies to reduce the latent reservoir. In this study, we quantif...

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Publicado en:AIDS Res Hum Retroviruses
Autores principales: Saha, Jamaluddin Md, Liu, Hongbing, Hu, Pei-Wen, Nikolai, Bryan C., Wu, Hulin, Miao, Hongyu, Rice, Andrew P.
Formato: Artigo
Lenguaje:Inglês
Publicado: Mary Ann Liebert, Inc. 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771535/
https://ncbi.nlm.nih.gov/pubmed/29084447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2017.0077
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