Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea

Por Unemo, Magnus, Nicholas, Robert A
Publicado em 2012

Identification and Analysis of Amino Acid Mutations in Porin IB That Mediate Intermediate-Level Resistance to Penicillin and Tetracycline in Neisseria gonorrhoeae

Por Olesky, Melanie, Hobbs, Marcia, Nicholas, Robert A.
Publicado em 2002

Unusual conformation of the SxN motif in the crystal structure of penicillin-binding protein A from Mycobacterium tuberculosis

Por Fedarovich, Alena, Nicholas, Robert A., Davies, Christopher
Publicado em 2010

The role of the β5-α11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis

Por Fedarovich, Alena, Nicholas, Robert A., Davies, Christopher
Publicado em 2012

GPR80/99, proposed to be the P2Y(15) receptor activated by adenosine and AMP, is not a P2Y receptor

Por Qi, Ai-Dong, Harden, T. Kendall, Nicholas, Robert A.
Publicado em 2004

Neisseria gonorrhoeae Penicillin-Binding Protein 3 Demonstrates a Pronounced Preference for N(ε)-Acylated Substrates

Por Peddi, Sridhar, Nicholas, Robert A., Gutheil, William G.
Publicado em 2009

Is GPR17 a P2Y/Leukotriene Receptor? Examination of Uracil Nucleotides, Nucleotide Sugars, and Cysteinyl Leukotrienes as Agonists of GPR17

Por Qi, Ai-Dong, Harden, T. Kendall, Nicholas, Robert A.
Publicado em 2013

UTP is not a biased agonist at human P2Y(11) receptors

Por Morrow, Gael B., Nicholas, Robert A., Kennedy, Charles
Publicado no Purinergic Signal (2014)

Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

Por Veal, Wendy L., Nicholas, Robert A., Shafer, William M.
Publicado em 2002

High-Level Chromosomally Mediated Tetracycline Resistance in Neisseria gonorrhoeae Results from a Point Mutation in the rpsJ Gene Encoding Ribosomal Protein S10 in Combination with...

Por Hu, Mei, Nandi, Sobhan, Davies, Christopher, Nicholas, Robert A.
Publicado em 2005

A large displacement of the SXN motif of Cys(115)-modified penicillin-binding protein 5 from Escherichia coli

Por Nicola, George, Fedarovich, Alena, Nicholas, Robert A., Davies, Christopher
Publicado em 2005

Interaction energies between β-lactam antibiotics and E. coli penicillin-binding protein 5 by reversible thermal denaturation

Por Beadle, Beth M., Nicholas, Robert A., Shoichet, Brian K.
Publicado em 2001

Molecular and structural analysis of mosaic variants of penicillin-binding protein 2 conferring decreased susceptibility to expanded-spectrum cephalosporins in Neisseria gonorrhoea...

Por Tomberg, Joshua, Unemo, Magnus, Davies, Christopher, Nicholas, Robert A
Publicado em 2010

Diffusion of Antibiotics through the PilQ Secretin in Neisseria gonorrhoeae Occurs through the Immature, Sodium Dodecyl Sulfate-Labile Form

Por Nandi, Sobhan, Swanson, Shauna, Tomberg, Joshua, Nicholas, Robert A.
Publicado no J Bacteriol (2015)

Complete Genome Sequences of Three Neisseria gonorrhoeae Laboratory Reference Strains, Determined Using PacBio Single-Molecule Real-Time Technology

Por Abrams, A. Jeanine, Trees, David L., Nicholas, Robert A.
Publicado no Genome Announc (2015)

Mutations in ponA, the Gene Encoding Penicillin-Binding Protein 1, and a Novel Locus, penC, Are Required for High-Level Chromosomally Mediated Penicillin Resistance in Neisseria go...

Por Ropp, Patricia A., Hu, Mei, Olesky, Melanie, Nicholas, Robert A.
Publicado em 2002

Porin-Mediated Antibiotic Resistance in Neisseria gonorrhoeae: Ion, Solute, and Antibiotic Permeation through PIB Proteins with penB Mutations

Por Olesky, Melanie, Zhao, Shuqing, Rosenberg, Robert L., Nicholas, Robert A.
Publicado em 2006

Differential coupling of the human P2Y(11) receptor to phospholipase C and adenylyl cyclase

Por Qi, Ai-Dong, Kennedy, Charles, Harden, T Kendall, Nicholas, Robert A
Publicado em 2001

P2Y(1) receptor modulation of endogenous ion channel function in Xenopus oocytes: Involvement of transmembrane domains

Por Lee, So Yeong, Nicholas, Robert A., O’Grady, Scott M.
Publicado em 2004

Genotyping as a Tool for Antibiotic Resistance Surveillance of Neisseria gonorrhoeae in New Caledonia: Evidence of a Novel Genotype Associated with Reduced Penicillin Susceptibilit...

Por Vernel-Pauillac, Frédérique, Nandi, Sobhan, Nicholas, Robert A., Goarant, Cyrille
Publicado em 2008