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Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae
The importance of the mtrCDE-encoded efflux pump in conferring chromosomally mediated penicillin resistance on certain strains of Neisseria gonorrhoeae was determined by using genetic derivatives of penicillin-sensitive strain FA19 bearing defined mutations (mtrR, penA, and penB) donated by a clinic...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2002
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC139619/ https://ncbi.nlm.nih.gov/pubmed/12270819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.184.20.5619-5624.2002 |
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