Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

Eitemau Tebyg

• Clinically Relevant Mutations that Cause Derepression of the Neisseria gonorrhoeae MtrC-MtrD-MtrE Efflux Pump System Confer Different Levels of Antimicrobial Resistance and In Vivo Fitness
  gan: Warner, Douglas M., et al.
  Cyhoeddwyd: (2008)
• The MtrR repressor binds the DNA sequence between the mtrR and mtrC genes of Neisseria gonorrhoeae.
  gan: Lucas, C E, et al.
  Cyhoeddwyd: (1997)
• Crystal Structure of the Neisseria gonorrhoeae MtrD Inner Membrane Multidrug Efflux Pump
  gan: Bolla, Jani Reddy, et al.
  Cyhoeddwyd: (2014)
• Inducible, but Not Constitutive, Resistance of Gonococci to Hydrophobic Agents Due to the MtrC-MtrD-MtrE Efflux Pump Requires TonB-ExbB-ExbD Proteins
  gan: Rouquette-Loughlin, Corinne, et al.
  Cyhoeddwyd: (2002)
• Modulation of the Neisseria gonorrhoeae drug efflux conduit MtrE
  gan: Tamburrino, Giulia, et al.
  Cyhoeddwyd: (2017)