Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

The importance of the mtrCDE-encoded efflux pump in conferring chromosomally mediated penicillin resistance on certain strains of Neisseria gonorrhoeae was determined by using genetic derivatives of penicillin-sensitive strain FA19 bearing defined mutations (mtrR, penA, and penB) donated by a clinic...

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Bibliografiske detaljer

Udgivet i:	J Bacteriol
Principais autores:	Veal, Wendy L., Nicholas, Robert A., Shafer, William M.
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 2002
Fag:	Molecular Biology of Pathogens
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139619/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12270819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.20.5619-5624.2002
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