Overexpression of the MtrC-MtrD-MtrE Efflux Pump Due to an mtrR Mutation Is Required for Chromosomally Mediated Penicillin Resistance in Neisseria gonorrhoeae

The importance of the mtrCDE-encoded efflux pump in conferring chromosomally mediated penicillin resistance on certain strains of Neisseria gonorrhoeae was determined by using genetic derivatives of penicillin-sensitive strain FA19 bearing defined mutations (mtrR, penA, and penB) donated by a clinic...

Full description

Bibliographic Details

Published in:	J Bacteriol
Main Authors:	Veal, Wendy L., Nicholas, Robert A., Shafer, William M.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Molecular Biology of Pathogens
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC139619/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12270819/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.184.20.5619-5624.2002
Tags:	Add Tag No Tags, Be the first to tag this record!