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The role of the β5-α11 loop in the active-site dynamics of acylated penicillin-binding protein A from Mycobacterium tuberculosis

Penicillin-binding protein A (PBPA) is a class B penicillin-binding protein that is important for cell division in M. tuberculosis. We have determined a second crystal structure of PBPA in apo form and compared it with an earlier structure of the apo enzyme. Significant structural differences in the...

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Detalhes bibliográficos
Main Authors: Fedarovich, Alena, Nicholas, Robert A., Davies, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3327805/
https://ncbi.nlm.nih.gov/pubmed/22365933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2012.02.021
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