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UTP is not a biased agonist at human P2Y(11) receptors
Biased agonism describes a multistate model of G protein-coupled receptor activation in which each ligand induces a unique structural conformation of the receptor, such that the receptor couples differentially to G proteins and other intracellular proteins. P2Y receptors are G protein-coupled recept...
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| Publicado no: | Purinergic Signal |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272372/ https://ncbi.nlm.nih.gov/pubmed/25015314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-014-9418-3 |
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