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Characterisation of P2Y(2) receptors in human vascular endothelial cells using AR‐C118925XX, a competitive and selective P2Y(2) antagonist

BACKGROUND AND PURPOSE: There is a lack of potent, selective antagonists at most subtypes of P2Y receptor. The aims of this study were to characterise the pharmacological properties of the proposed P2Y(2) receptor antagonist, AR‐C118925XX, and then to use it to determine the role of P2Y(2) receptors...

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Dades bibliogràfiques
Publicat a:Br J Pharmacol
Autors principals: Muoboghare, Markie O., Drummond, Robert M., Kennedy, Charles
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6637037/
https://ncbi.nlm.nih.gov/pubmed/31116875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14715
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