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UDP Is a Competitive Antagonist at the Human P2Y(14) Receptor

G protein-coupled P2Y receptors (P2Y-R) are activated by adenine and uracil nucleotides. The P2Y(14) receptor (P2Y(14)-R) is activated by at least four naturally occurring UDP sugars, with UDP-glucose (UDP-Glc) being the most potent agonist. With the goal of identifying a competitive antagonist for...

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Autori principali: Fricks, Ingrid P., Maddileti, Savitri, Carter, Rhonda L., Lazarowski, Eduardo R., Nicholas, Robert A., Jacobson, Kenneth A., Harden, T. Kendall
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2918431/
https://ncbi.nlm.nih.gov/pubmed/18252808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.136309
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