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Synthesis, characterization, and in vitro evaluation of the selective P2Y(2) receptor antagonist AR-C118925

The G(q) protein-coupled, ATP- and UTP-activated P2Y(2) receptor is a potential drug target for a range of different disorders, including tumor metastasis, inflammation, atherosclerosis, kidney disorders, and osteoporosis, but pharmacological studies are impeded by the limited availability of suitab...

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Detalhes bibliográficos
Publicado no:Purinergic Signal
Main Authors: Rafehi, Muhammad, Burbiel, Joachim C., Attah, Isaac Y., Abdelrahman, Aliaa, Müller, Christa E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5334202/
https://ncbi.nlm.nih.gov/pubmed/27766552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-016-9542-3
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