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Microwave-assisted ring closure reactions: Synthesis of 8-substituted xanthine derivatives and related pyrimido- and diazepinopurinediones

BACKGROUND: Poly-substituted xanthine derivatives are an important class of compounds in medicinal chemistry. Substitution at the 8-position of the purine ring is generally accessible by ring closure of a carboxamido-substituted uracil precursor. Although several procedures to accomplish this synthe...

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Autors principals: Burbiel, Joachim C, Hockemeyer, Jörg, Müller, Christa E
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698928/
https://ncbi.nlm.nih.gov/pubmed/17067400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1860-5397-2-20
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